Drug interactions
Calcium carbonate + Cefditoren
Severity: Moderate
Calcium carbonate and Cefditoren: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefditoren absorption depends on gastric acidity, and acid-reducing agents lower its exposure. Calcium carbonate raises gastric pH and may reduce cefditoren efficacy.
What this interaction means in plain words
Calcium carbonate and Cefditoren can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Cefditoren belongs to Anti Bacterial.
Why it happens
Increased gastric pH reduces cefditoren absorption.
What to do
Avoid concurrent use of antacids with cefditoren where possible; if needed, separate by about 2 hours and watch for treatment failure.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium carbonate
Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
- Cefditoren + Famotidine Moderate
Frequently asked questions
Can I take Calcium carbonate with Cefditoren?
MediHelp rates the interaction as moderate. Calcium carbonate and Cefditoren can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefditoren absorption depends on gastric acidity, and acid-reducing agents lower its exposure. Calcium carbonate raises gastric pH and may reduce cefditoren efficacy.
How serious is the interaction between Calcium carbonate and Cefditoren?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of antacids with cefditoren where possible; if needed, separate by about 2 hours and watch for treatment failure.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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