Drug interactions
Cefditoren + Dexlansoprazole
Severity: Moderate
Cefditoren and Dexlansoprazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Acid suppression reduces absorption of cefditoren pivoxil, lowering antibiotic exposure and possibly causing treatment failure. The label advises against combining it with acid-reducing drugs.
What this interaction means in plain words
Cefditoren and Dexlansoprazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefditoren belongs to Anti Bacterial; Dexlansoprazole belongs to Gastrointestinal Tract.
Why it happens
Higher gastric pH reduces the absorption of cefditoren pivoxil.
What to do
Choose a different antibiotic that is not affected by gastric pH, or monitor clinical response closely if the combination is unavoidable.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dexlansoprazole
- Dexlansoprazole + Mavacamten Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Dexlansoprazole Major
- Atazanavir + Dexlansoprazole Major
- Dacomitinib + Dexlansoprazole Major
- Dasatinib + Dexlansoprazole Major
Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Famotidine Moderate
Frequently asked questions
Can I take Cefditoren with Dexlansoprazole?
MediHelp rates the interaction as moderate. Cefditoren and Dexlansoprazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Acid suppression reduces absorption of cefditoren pivoxil, lowering antibiotic exposure and possibly causing treatment failure. The label advises against combining it with acid-reducing drugs.
How serious is the interaction between Cefditoren and Dexlansoprazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Choose a different antibiotic that is not affected by gastric pH, or monitor clinical response closely if the combination is unavoidable.
What other medicines interact with Dexlansoprazole?
MediHelp also lists interactions of Dexlansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Dexlansoprazole page.
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