Drug interactions
Aminolevulinic acid + Flurbiprofen
Severity: Minor
Aminolevulinic acid and Flurbiprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral aminolevulinic acid causes photosensitivity, and other agents with phototoxic potential could add to the risk of skin reactions. Flurbiprofen has low photosensitizing potential, so the interaction is mostly theoretical.
What this interaction means in plain words
Aminolevulinic acid and Flurbiprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aminolevulinic acid belongs to Miscellaneous; Flurbiprofen belongs to Musculoskeletal.
Why it happens
Possible additive photosensitization from protoporphyrin accumulation and drug phototoxicity.
What to do
Counsel the patient to avoid sunlight and bright light for the period in the aminolevulinic acid labeling. Consider paracetamol as an alternative during that period.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Aminolevulinic acid
- Acitretin + Aminolevulinic acid Major
- Aminolevulinic acid + Doxycycline Major
- Aminolevulinic acid + Isotretinoin Major
- Aminolevulinic acid + Amiodarone Moderate
- Aminolevulinic acid + Amlodipine-hydrochlorothiazide-valsartan Moderate
- Aminolevulinic acid + Amlodipine-olmesartan-hydrochlorothiazide Moderate
Frequently asked questions
Can I take Aminolevulinic acid with Flurbiprofen?
MediHelp rates the interaction as minor. Aminolevulinic acid and Flurbiprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral aminolevulinic acid causes photosensitivity, and other agents with phototoxic potential could add to the risk of skin reactions. Flurbiprofen has low photosensitizing potential, so the interaction is mostly theoretical.
How serious is the interaction between Aminolevulinic acid and Flurbiprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to avoid sunlight and bright light for the period in the aminolevulinic acid labeling. Consider paracetamol as an alternative during that period.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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