Drug interactions
Aminolevulinic acid + Ofloxacin
Severity: Moderate
Aminolevulinic acid and Ofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ofloxacin can cause phototoxicity, and oral aminolevulinic acid used for surgical visualization causes photosensitivity. Together they may increase the risk of skin phototoxic reactions after exposure to light.
What this interaction means in plain words
Aminolevulinic acid and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aminolevulinic acid belongs to Miscellaneous; Ofloxacin belongs to Anti Bacterial.
Why it happens
Additive photosensitization.
What to do
Avoid other phototoxic drugs for the labeled period around aminolevulinic acid use, and advise protection from sunlight and bright indoor light.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Other interactions of Aminolevulinic acid
- Acitretin + Aminolevulinic acid Major
- Aminolevulinic acid + Doxycycline Major
- Aminolevulinic acid + Isotretinoin Major
- Aminolevulinic acid + Amiodarone Moderate
- Aminolevulinic acid + Amlodipine-hydrochlorothiazide-valsartan Moderate
- Aminolevulinic acid + Amlodipine-olmesartan-hydrochlorothiazide Moderate
Frequently asked questions
Can I take Aminolevulinic acid with Ofloxacin?
MediHelp rates the interaction as moderate. Aminolevulinic acid and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ofloxacin can cause phototoxicity, and oral aminolevulinic acid used for surgical visualization causes photosensitivity. Together they may increase the risk of skin phototoxic reactions after exposure to light.
How serious is the interaction between Aminolevulinic acid and Ofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid other phototoxic drugs for the labeled period around aminolevulinic acid use, and advise protection from sunlight and bright indoor light.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
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