Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Dicloxacillin
Severity: Minor
Amlodipine-olmesartan-hydrochlorothiazide and Dicloxacillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazides and penicillins are both eliminated by renal tubular secretion, so some competition is theoretically possible. Clinically significant changes in either drug have not been established.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Dicloxacillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Dicloxacillin belongs to Anti Bacterial.
Why it happens
Possible competition for renal tubular organic anion secretion; clinical relevance is unproven.
What to do
No routine action is needed. Monitor for efficacy of the antibiotic in severe infections and for blood pressure and electrolyte changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Other interactions of Dicloxacillin
- Dicloxacillin + Phenindione Major
- Atogepant + Dicloxacillin Moderate
- Axitinib + Dicloxacillin Moderate
- Bcg vaccine live + Dicloxacillin Moderate
- Cholera vaccine + Dicloxacillin Moderate
- Demeclocycline + Dicloxacillin Moderate
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Dicloxacillin?
MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Dicloxacillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazides and penicillins are both eliminated by renal tubular secretion, so some competition is theoretically possible. Clinically significant changes in either drug have not been established.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Dicloxacillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor for efficacy of the antibiotic in severe infections and for blood pressure and electrolyte changes.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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