Drug interactions
Amlodipine-perindopril + Etrasimod
Severity: Minor
Amlodipine-perindopril and Etrasimod: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod can cause transient heart rate reduction and atrioventricular conduction delay when treatment begins. Amlodipine is a dihydropyridine with little direct effect on heart rate, so the additive risk is low, but caution applies to other agents that slow conduction.
What this interaction means in plain words
Amlodipine-perindopril and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-perindopril belongs to Cardiovascular; Etrasimod belongs to Gastrointestinal Tract.
Why it happens
Possible additive hemodynamic effects, but amlodipine has minimal effect on cardiac conduction.
What to do
Follow the standard etrasimod first-dose monitoring recommendations. Review heart rate if other rate-lowering drugs are added.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-perindopril
- Aliskiren + Amlodipine-perindopril Contraindicated
- Amlodipine-perindopril + Protein a column Contraindicated
- Amlodipine-perindopril + Sacubitril / valsartan Contraindicated
- Amifostine + Amlodipine-perindopril Major
- Amiloride + Amlodipine-perindopril Major
- Amlodipine-perindopril + Azilsartan Major
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Amlodipine-perindopril with Etrasimod?
MediHelp rates the interaction as minor. Amlodipine-perindopril and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etrasimod can cause transient heart rate reduction and atrioventricular conduction delay when treatment begins. Amlodipine is a dihydropyridine with little direct effect on heart rate, so the additive risk is low, but caution applies to other agents that slow conduction.
How serious is the interaction between Amlodipine-perindopril and Etrasimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Follow the standard etrasimod first-dose monitoring recommendations. Review heart rate if other rate-lowering drugs are added.
What other medicines interact with Amlodipine-perindopril?
MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Amlodipine-perindopril page.
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