Drug interactions
Amobarbital + Dalteparin
Severity: Minor
Amobarbital and Dalteparin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Barbiturate enzyme induction is not expected to reduce dalteparin activity, since it is mainly renally cleared and not a CYP substrate. No clinically meaningful interaction is established.
What this interaction means in plain words
Amobarbital and Dalteparin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amobarbital belongs to Central Nervous System; Dalteparin belongs to Cardiovascular.
Why it happens
No established mechanism; dalteparin is not metabolized by inducible CYP enzymes.
What to do
No dose adjustment; monitor anti-Xa only if otherwise indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Other interactions of Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Amobarbital + Doravirine Contraindicated
- Amobarbital + Elbasvir / grazoprevir Contraindicated
- Amobarbital + Isavuconazonium Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amobarbital + Lonafarnib Contraindicated
Frequently asked questions
Can I take Amobarbital with Dalteparin?
MediHelp rates the interaction as minor. Amobarbital and Dalteparin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Barbiturate enzyme induction is not expected to reduce dalteparin activity, since it is mainly renally cleared and not a CYP substrate. No clinically meaningful interaction is established.
How serious is the interaction between Amobarbital and Dalteparin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment; monitor anti-Xa only if otherwise indicated.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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