Drug interactions
Aripiprazole + Dolasetron
Severity: Minor
Aripiprazole and Dolasetron: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dolasetron prolongs the QT interval in a dose-related way, and aripiprazole has a small QT liability. Combined use adds modestly to the risk of arrhythmia, mainly in patients with other risk factors.
What this interaction means in plain words
Aripiprazole and Dolasetron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Dolasetron belongs to Gastrointestinal Tract.
Why it happens
Additive, small QT prolongation effects.
What to do
No routine change is needed; check ECG and electrolytes in patients with other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dolasetron
- Apomorphine + Dolasetron Contraindicated
- Dofetilide + Dolasetron Contraindicated
- Dolasetron + Ibutilide Contraindicated
- Dolasetron + Pimozide Contraindicated
- Dolasetron + Thioridazine Contraindicated
- Dolasetron + Vandetanib Contraindicated
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Dolasetron?
MediHelp rates the interaction as minor. Aripiprazole and Dolasetron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dolasetron prolongs the QT interval in a dose-related way, and aripiprazole has a small QT liability. Combined use adds modestly to the risk of arrhythmia, mainly in patients with other risk factors.
How serious is the interaction between Aripiprazole and Dolasetron?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; check ECG and electrolytes in patients with other QT risk factors.
What other medicines interact with Dolasetron?
MediHelp also lists interactions of Dolasetron with, for example, Apomorphine, Dofetilide, Ibutilide. The full list is on the Dolasetron page.
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