Drug interactions
Aripiprazole + Ozanimod
Severity: Minor
Aripiprazole and Ozanimod: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod can slow heart rate and affect cardiac conduction, and aripiprazole may add a small QT effect. The combination calls for attention in patients with arrhythmia risk, though the clinical significance is uncertain.
What this interaction means in plain words
Aripiprazole and Ozanimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Ozanimod belongs to Central Nervous System.
Why it happens
Possible additive effects on cardiac conduction and repolarization; the mechanism is not firmly established.
What to do
Perform a baseline ECG before starting ozanimod, and monitor heart rate and QTc in patients with cardiac risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Aripiprazole with Ozanimod?
MediHelp rates the interaction as minor. Aripiprazole and Ozanimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ozanimod can slow heart rate and affect cardiac conduction, and aripiprazole may add a small QT effect. The combination calls for attention in patients with arrhythmia risk, though the clinical significance is uncertain.
How serious is the interaction between Aripiprazole and Ozanimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform a baseline ECG before starting ozanimod, and monitor heart rate and QTc in patients with cardiac risk factors.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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