Drug interactions
Aripiprazole + Tiotropium-olodaterol
Severity: Minor
Aripiprazole and Tiotropium-olodaterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aripiprazole has a low QT liability, but olodaterol can cause tachycardia and hypokalemia. Aripiprazole has little anticholinergic activity, so a significant interaction with tiotropium is unlikely.
What this interaction means in plain words
Aripiprazole and Tiotropium-olodaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Tiotropium-olodaterol belongs to Respiratory.
Why it happens
No well-established mechanism; only a theoretical additive cardiac effect.
What to do
No specific action is needed; monitor heart rate and rhythm in patients with cardiac risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tiotropium-olodaterol
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Tiotropium-olodaterol?
MediHelp rates the interaction as minor. Aripiprazole and Tiotropium-olodaterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aripiprazole has a low QT liability, but olodaterol can cause tachycardia and hypokalemia. Aripiprazole has little anticholinergic activity, so a significant interaction with tiotropium is unlikely.
How serious is the interaction between Aripiprazole and Tiotropium-olodaterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor heart rate and rhythm in patients with cardiac risk factors.
What other medicines interact with Tiotropium-olodaterol?
MediHelp also lists interactions of Tiotropium-olodaterol with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Tiotropium-olodaterol page.
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