Drug interactions
Aripiprazole + Triclabendazole
Severity: Moderate
Aripiprazole and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole can prolong the QT interval and aripiprazole has a low QT liability, so additive effect is possible. The risk is greatest with electrolyte disturbances or other QT-prolonging drugs.
What this interaction means in plain words
Aripiprazole and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aripiprazole belongs to Central Nervous System; Triclabendazole belongs to Anti Parasitic.
Why it happens
Possible additive QT interval prolongation.
What to do
Check baseline ECG and electrolytes in at-risk patients and correct hypokalemia or hypomagnesemia. Consider alternatives if QTc becomes markedly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Aripiprazole with Triclabendazole?
MediHelp rates the interaction as moderate. Aripiprazole and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole can prolong the QT interval and aripiprazole has a low QT liability, so additive effect is possible. The risk is greatest with electrolyte disturbances or other QT-prolonging drugs.
How serious is the interaction between Aripiprazole and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in at-risk patients and correct hypokalemia or hypomagnesemia. Consider alternatives if QTc becomes markedly prolonged.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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