Drug interactions
Armodafinil + Dutasteride-tamsulosin
Severity: Minor
Armodafinil and Dutasteride-tamsulosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil is a weak CYP3A4 inducer and could modestly lower dutasteride exposure, which is cleared by CYP3A4. The clinical consequence is likely small and is predicted rather than demonstrated.
What this interaction means in plain words
Armodafinil and Dutasteride-tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Dutasteride-tamsulosin belongs to Genitourinary.
Why it happens
Weak induction of CYP3A4 by armodafinil may increase dutasteride metabolism.
What to do
No dose change is needed; assess clinical response to dutasteride over time if armodafinil is used long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dutasteride-tamsulosin
Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Dutasteride-tamsulosin?
MediHelp rates the interaction as minor. Armodafinil and Dutasteride-tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil is a weak CYP3A4 inducer and could modestly lower dutasteride exposure, which is cleared by CYP3A4. The clinical consequence is likely small and is predicted rather than demonstrated.
How serious is the interaction between Armodafinil and Dutasteride-tamsulosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; assess clinical response to dutasteride over time if armodafinil is used long term.
What other medicines interact with Dutasteride-tamsulosin?
MediHelp also lists interactions of Dutasteride-tamsulosin with, for example, Alfuzosin, Amifostine, Atazanavir. The full list is on the Dutasteride-tamsulosin page.
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