Drug interactions
Armodafinil + Felodipine
Severity: Minor
Armodafinil and Felodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil is a weak CYP3A4 inducer and may modestly lower felodipine exposure, with possible reduced blood pressure control. The effect is generally small.
What this interaction means in plain words
Armodafinil and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Felodipine belongs to Cardiovascular.
Why it happens
Weak induction of CYP3A4 by armodafinil increases felodipine metabolism.
What to do
Monitor blood pressure after starting or stopping armodafinil and adjust felodipine if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Other interactions of Armodafinil
Frequently asked questions
Can I take Armodafinil with Felodipine?
MediHelp rates the interaction as minor. Armodafinil and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil is a weak CYP3A4 inducer and may modestly lower felodipine exposure, with possible reduced blood pressure control. The effect is generally small.
How serious is the interaction between Armodafinil and Felodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure after starting or stopping armodafinil and adjust felodipine if control changes.
What other medicines interact with Felodipine?
MediHelp also lists interactions of Felodipine with, for example, Itraconazole, Aldesleukin, Amifostine. The full list is on the Felodipine page.
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