Drug interactions
Armodafinil + Fruquintinib
Severity: Minor
Armodafinil and Fruquintinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fruquintinib is partly metabolized by CYP3A4, so armodafinil may lower its exposure. Labeling indicates moderate inducers do not require dose changes.
What this interaction means in plain words
Armodafinil and Fruquintinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Armodafinil belongs to Central Nervous System; Fruquintinib belongs to Oncology.
Why it happens
Armodafinil induces CYP3A4, modestly increasing the metabolism of fruquintinib.
What to do
Continue fruquintinib at the recommended dose and monitor tumor response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Armodafinil
Other interactions of Fruquintinib
- Amobarbital + Fruquintinib Major
- Apalutamide + Fruquintinib Major
- Carbamazepine + Fruquintinib Major
- Enzalutamide + Fruquintinib Major
- Fruquintinib + Phenytoin Major
- Bosentan + Fruquintinib Moderate
Frequently asked questions
Can I take Armodafinil with Fruquintinib?
MediHelp rates the interaction as minor. Armodafinil and Fruquintinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fruquintinib is partly metabolized by CYP3A4, so armodafinil may lower its exposure. Labeling indicates moderate inducers do not require dose changes.
How serious is the interaction between Armodafinil and Fruquintinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue fruquintinib at the recommended dose and monitor tumor response.
What other medicines interact with Armodafinil?
MediHelp also lists interactions of Armodafinil with, for example, Avapritinib, Elacestrant, Elbasvir / grazoprevir. The full list is on the Armodafinil page.
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