Drug interactions
Atazanavir + Ixazomib
Severity: Minor
Atazanavir and Ixazomib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atazanavir inhibits CYP3A4, but in clinical studies strong CYP3A inhibition did not produce a meaningful change in ixazomib exposure. No clinically important interaction is expected.
What this interaction means in plain words
Atazanavir and Ixazomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atazanavir belongs to Anti Virals; Ixazomib belongs to Oncology.
Why it happens
Atazanavir inhibits CYP3A4, but this pathway contributes little to overall ixazomib clearance.
What to do
No dose adjustment is needed; monitor routinely for ixazomib adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ixazomib
- Apalutamide + Ixazomib Major
- Carbamazepine + Ixazomib Major
- Dabrafenib + Ixazomib Major
- Enzalutamide + Ixazomib Major
- Etrasimod + Ixazomib Major
- Fosphenytoin + Ixazomib Major
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Ixazomib?
MediHelp rates the interaction as minor. Atazanavir and Ixazomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atazanavir inhibits CYP3A4, but in clinical studies strong CYP3A inhibition did not produce a meaningful change in ixazomib exposure. No clinically important interaction is expected.
How serious is the interaction between Atazanavir and Ixazomib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor routinely for ixazomib adverse effects.
What other medicines interact with Ixazomib?
MediHelp also lists interactions of Ixazomib with, for example, Apalutamide, Carbamazepine, Dabrafenib. The full list is on the Ixazomib page.
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