Drug interactions
Atogepant + Bicalutamide
Severity: Minor
Atogepant and Bicalutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bicalutamide is at most a weak CYP3A4 inhibitor in vivo, so a meaningful rise in atogepant levels is unlikely. The interaction is largely theoretical.
What this interaction means in plain words
Atogepant and Bicalutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atogepant belongs to Central Nervous System; Bicalutamide belongs to Endocrine.
Why it happens
Weak, poorly established CYP3A4 inhibition by bicalutamide.
What to do
No dose adjustment needed; monitor for atogepant adverse effects such as constipation and nausea.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bicalutamide
- Bicalutamide + Lomitapide Major
- Aminolevulinic acid + Bicalutamide Moderate
- Bicalutamide + Eliglustat Moderate
- Bicalutamide + Flibanserin Moderate
- Bicalutamide + Ivosidenib Moderate
- Bicalutamide + Lonafarnib Moderate
Other interactions of Atogepant
- Amobarbital + Atogepant Moderate
- Apalutamide + Atogepant Moderate
- Aprepitant + Atogepant Moderate
- Armodafinil + Atogepant Moderate
- Atogepant + Bosentan Moderate
- Atogepant + Carbamazepine Moderate
Frequently asked questions
Can I take Atogepant with Bicalutamide?
MediHelp rates the interaction as minor. Atogepant and Bicalutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bicalutamide is at most a weak CYP3A4 inhibitor in vivo, so a meaningful rise in atogepant levels is unlikely. The interaction is largely theoretical.
How serious is the interaction between Atogepant and Bicalutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment needed; monitor for atogepant adverse effects such as constipation and nausea.
What other medicines interact with Bicalutamide?
MediHelp also lists interactions of Bicalutamide with, for example, Lomitapide, Aminolevulinic acid, Eliglustat. The full list is on the Bicalutamide page.
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