Drug interactions
Atogepant + Bortezomib
Severity: Minor
Atogepant and Bortezomib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bortezomib is not a recognized clinically relevant CYP3A4 inhibitor, so a meaningful rise in atogepant exposure is not expected. The interaction is theoretical.
What this interaction means in plain words
Atogepant and Bortezomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atogepant belongs to Central Nervous System; Bortezomib belongs to Oncology.
Why it happens
Not established; bortezomib is a CYP3A4 substrate and not a clinically significant inhibitor.
What to do
No dose adjustment is needed. Monitor for atogepant adverse effects such as nausea and constipation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bortezomib
- Apalutamide + Bortezomib Major
- Bortezomib + Carbamazepine Major
- Bortezomib + Etrasimod Major
- Bortezomib + Fosphenytoin Major
- Bortezomib + Idelalisib Major
- Bortezomib + Lonafarnib Major
Other interactions of Atogepant
- Amobarbital + Atogepant Moderate
- Apalutamide + Atogepant Moderate
- Aprepitant + Atogepant Moderate
- Armodafinil + Atogepant Moderate
- Atogepant + Bosentan Moderate
- Atogepant + Carbamazepine Moderate
Frequently asked questions
Can I take Atogepant with Bortezomib?
MediHelp rates the interaction as minor. Atogepant and Bortezomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bortezomib is not a recognized clinically relevant CYP3A4 inhibitor, so a meaningful rise in atogepant exposure is not expected. The interaction is theoretical.
How serious is the interaction between Atogepant and Bortezomib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor for atogepant adverse effects such as nausea and constipation.
What other medicines interact with Bortezomib?
MediHelp also lists interactions of Bortezomib with, for example, Apalutamide, Carbamazepine, Etrasimod. The full list is on the Bortezomib page.
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