Drug interactions
Atogepant + Haloperidol
Severity: Minor
Atogepant and Haloperidol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atogepant is cleared mainly by CYP3A4, and haloperidol is only a weak CYP3A4 inhibitor, so any rise in atogepant exposure is likely small. A clinically meaningful interaction is not established.
What this interaction means in plain words
Atogepant and Haloperidol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atogepant belongs to Central Nervous System; Haloperidol belongs to Central Nervous System.
Why it happens
Possible weak CYP3A4 inhibition by haloperidol; not clearly established.
What to do
No dose adjustment is generally needed; monitor for atogepant adverse effects such as nausea, constipation and fatigue.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Atogepant
- Amobarbital + Atogepant Moderate
- Apalutamide + Atogepant Moderate
- Aprepitant + Atogepant Moderate
- Armodafinil + Atogepant Moderate
- Atogepant + Bosentan Moderate
- Atogepant + Carbamazepine Moderate
Frequently asked questions
Can I take Atogepant with Haloperidol?
MediHelp rates the interaction as minor. Atogepant and Haloperidol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atogepant is cleared mainly by CYP3A4, and haloperidol is only a weak CYP3A4 inhibitor, so any rise in atogepant exposure is likely small. A clinically meaningful interaction is not established.
How serious is the interaction between Atogepant and Haloperidol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is generally needed; monitor for atogepant adverse effects such as nausea, constipation and fatigue.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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