Drug interactions
Axitinib + Ticlopidine
Severity: Minor
Axitinib and Ticlopidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ticlopidine is not a strong CYP3A4 inhibitor, so a meaningful rise in axitinib exposure is unlikely. The pairing is mainly theoretical.
What this interaction means in plain words
Axitinib and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Axitinib belongs to Oncology; Ticlopidine belongs to Cardiovascular.
Why it happens
Possible weak CYP3A4 inhibition; not an established effect of ticlopidine.
What to do
No dose adjustment is needed; monitor for axitinib adverse effects such as hypertension and bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ticlopidine
Other interactions of Axitinib
- Amobarbital + Axitinib Major
- Apalutamide + Axitinib Major
- Atazanavir + Axitinib Major
- Axitinib + Carbamazepine Major
- Axitinib + Clarithromycin Major
- Axitinib + Cobicistat Major
Frequently asked questions
Can I take Axitinib with Ticlopidine?
MediHelp rates the interaction as minor. Axitinib and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ticlopidine is not a strong CYP3A4 inhibitor, so a meaningful rise in axitinib exposure is unlikely. The pairing is mainly theoretical.
How serious is the interaction between Axitinib and Ticlopidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor for axitinib adverse effects such as hypertension and bleeding.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
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