Drug interactions
Azilsartan-chlorthalidone + Miglitol
Severity: Minor
Azilsartan-chlorthalidone and Miglitol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlorthalidone may raise blood glucose and reduce the effect of miglitol. The effect is usually modest.
What this interaction means in plain words
Azilsartan-chlorthalidone and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan-chlorthalidone belongs to Cardiovascular; Miglitol belongs to Endocrine.
Why it happens
Thiazide-induced impairment of glucose tolerance opposes the antihyperglycemic effect (pharmacodynamic antagonism).
What to do
Monitor blood glucose after starting or changing chlorthalidone and adjust diabetes therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan-chlorthalidone
Other interactions of Miglitol
- Miglitol + Pramlintide Major
- Aripiprazole + Miglitol Moderate
- Asenapine + Miglitol Moderate
- Chlorthalidone + Miglitol Moderate
- Clozapine + Miglitol Moderate
- Cortisone + Miglitol Moderate
Frequently asked questions
Can I take Azilsartan-chlorthalidone with Miglitol?
MediHelp rates the interaction as minor. Azilsartan-chlorthalidone and Miglitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chlorthalidone may raise blood glucose and reduce the effect of miglitol. The effect is usually modest.
How serious is the interaction between Azilsartan-chlorthalidone and Miglitol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or changing chlorthalidone and adjust diabetes therapy if control worsens.
What other medicines interact with Azilsartan-chlorthalidone?
MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.
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