Drug interactions
Azithromycin + Indacaterol
Severity: Moderate
Azithromycin and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azithromycin can prolong the QT interval and has been linked to torsades de pointes. Indacaterol may add to this risk via tachycardia and potassium lowering.
What this interaction means in plain words
Azithromycin and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azithromycin belongs to Anti Bacterial; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation and beta-2 agonist related hypokalemia.
What to do
Monitor ECG in patients with QT risk factors and correct potassium and magnesium; consider a non-QT-prolonging antibiotic if the patient is high risk.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Frequently asked questions
Can I take Azithromycin with Indacaterol?
MediHelp rates the interaction as moderate. Azithromycin and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azithromycin can prolong the QT interval and has been linked to torsades de pointes. Indacaterol may add to this risk via tachycardia and potassium lowering.
How serious is the interaction between Azithromycin and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG in patients with QT risk factors and correct potassium and magnesium; consider a non-QT-prolonging antibiotic if the patient is high risk.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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