Drug interactions
Basiliximab + Human papillomavirus vaccine
Severity: Minor
Basiliximab and Human papillomavirus vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab blocks T-cell activation and might weaken the response to HPV vaccination. The non-live vaccine is safe, so the concern is only reduced immunogenicity.
What this interaction means in plain words
Basiliximab and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Basiliximab belongs to Miscellaneous; Human papillomavirus vaccine belongs to Miscellaneous.
Why it happens
IL-2 receptor blockade impairs T-cell dependent immune responses.
What to do
Vaccinate when clinically appropriate, ideally before transplant, and complete the three-dose series.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderate
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderate
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderate
- Belimumab + Human papillomavirus vaccine Moderate
- Cortisone + Human papillomavirus vaccine Moderate
- Cyclosporine + Human papillomavirus vaccine Moderate
Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Basiliximab with Human papillomavirus vaccine?
MediHelp rates the interaction as minor. Basiliximab and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Basiliximab blocks T-cell activation and might weaken the response to HPV vaccination. The non-live vaccine is safe, so the concern is only reduced immunogenicity.
How serious is the interaction between Basiliximab and Human papillomavirus vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate when clinically appropriate, ideally before transplant, and complete the three-dose series.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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