Drug interactions
Benazepril + Methamphetamine
Severity: Moderate
Benazepril and Methamphetamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Methamphetamine raises blood pressure through sympathomimetic effects and may counteract the antihypertensive effect of benazepril. Hypertension control may be compromised.
What this interaction means in plain words
Benazepril and Methamphetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Methamphetamine belongs to Central Nervous System.
Why it happens
Pharmacodynamic antagonism through sympathomimetic pressor effects.
What to do
Monitor blood pressure when methamphetamine is started or the dose changed. Adjust antihypertensive therapy if control is lost.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Benazepril with Methamphetamine?
MediHelp rates the interaction as moderate. Benazepril and Methamphetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Methamphetamine raises blood pressure through sympathomimetic effects and may counteract the antihypertensive effect of benazepril. Hypertension control may be compromised.
How serious is the interaction between Benazepril and Methamphetamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when methamphetamine is started or the dose changed. Adjust antihypertensive therapy if control is lost.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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