Drug interactions
Benazepril + Pentoxifylline
Severity: Minor
Benazepril and Pentoxifylline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pentoxifylline has vasodilating properties and has been associated with modest blood pressure reductions. Combined with benazepril it may enhance the antihypertensive effect, occasionally causing symptomatic hypotension.
What this interaction means in plain words
Benazepril and Pentoxifylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benazepril belongs to Cardiovascular; Pentoxifylline belongs to Cardiovascular.
Why it happens
Additive vasodilatory and blood pressure lowering effects.
What to do
Monitor blood pressure when pentoxifylline is added or the dose is changed. Reduce the antihypertensive dose only if hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Pentoxifylline
- Amifostine + Pentoxifylline Moderate
- Fluoxetine + Pentoxifylline Moderate
- Fluvoxamine + Pentoxifylline Moderate
- Insulin degludec / insulin aspart + Pentoxifylline Moderate
- Methoxsalen + Pentoxifylline Moderate
- Mexiletine + Pentoxifylline Moderate
Frequently asked questions
Can I take Benazepril with Pentoxifylline?
MediHelp rates the interaction as minor. Benazepril and Pentoxifylline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pentoxifylline has vasodilating properties and has been associated with modest blood pressure reductions. Combined with benazepril it may enhance the antihypertensive effect, occasionally causing symptomatic hypotension.
How serious is the interaction between Benazepril and Pentoxifylline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when pentoxifylline is added or the dose is changed. Reduce the antihypertensive dose only if hypotension occurs.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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