Drug interactions
Betaxolol + Silodosin
Severity: Minor
Betaxolol and Silodosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Silodosin can cause orthostatic hypotension and dizziness. Betaxolol, a beta-blocker, may add to the blood pressure reduction, particularly at initiation or after dose changes.
What this interaction means in plain words
Betaxolol and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Silodosin belongs to Genitourinary.
Why it happens
Additive pharmacodynamic hypotensive effects from alpha-1 adrenergic blockade and beta-adrenergic blockade.
What to do
Check standing blood pressure after starting or adjusting either drug and advise slow position changes. Lower the dose of one agent if symptomatic hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Silodosin
- Atazanavir + Silodosin Contraindicated
- Conivaptan + Silodosin Contraindicated
- Darunavir + Silodosin Contraindicated
- Fosamprenavir + Silodosin Contraindicated
- Indinavir + Silodosin Contraindicated
- Itraconazole + Silodosin Contraindicated
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Silodosin?
MediHelp rates the interaction as minor. Betaxolol and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Silodosin can cause orthostatic hypotension and dizziness. Betaxolol, a beta-blocker, may add to the blood pressure reduction, particularly at initiation or after dose changes.
How serious is the interaction between Betaxolol and Silodosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check standing blood pressure after starting or adjusting either drug and advise slow position changes. Lower the dose of one agent if symptomatic hypotension develops.
What other medicines interact with Silodosin?
MediHelp also lists interactions of Silodosin with, for example, Atazanavir, Conivaptan, Darunavir. The full list is on the Silodosin page.
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