Drug interactions
Bethanechol + Trazodone
Severity: Minor
Bethanechol and Trazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Trazodone has very little anticholinergic activity, so meaningful opposition to bethanechol is unlikely. Any interaction is theoretical.
What this interaction means in plain words
Bethanechol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bethanechol belongs to Gastrointestinal Tract; Trazodone belongs to Central Nervous System.
Why it happens
Weak muscarinic antagonism by trazodone; no established clinically relevant mechanism.
What to do
No specific action is needed. Reassess bethanechol response if efficacy appears reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bethanechol
- Bethanechol + Darifenacin Major
- Bethanechol + Fesoterodine Major
- Bethanechol + Oxybutynin Major
- Bethanechol + Physostigmine Major
- Amifampridine + Bethanechol Moderate
- Amitriptyline + Bethanechol Moderate
Other interactions of Trazodone
- Arsenic trioxide + Trazodone Contraindicated
- Ibutilide + Trazodone Contraindicated
- Isocarboxazid + Trazodone Contraindicated
- Levoketoconazole + Trazodone Contraindicated
- Methylene blue + Trazodone Contraindicated
- Phenelzine + Trazodone Contraindicated
Frequently asked questions
Can I take Bethanechol with Trazodone?
MediHelp rates the interaction as minor. Bethanechol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Trazodone has very little anticholinergic activity, so meaningful opposition to bethanechol is unlikely. Any interaction is theoretical.
How serious is the interaction between Bethanechol and Trazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Reassess bethanechol response if efficacy appears reduced.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
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