Drug interactions
Bortezomib + Flibanserin
Severity: Minor
Bortezomib and Flibanserin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bortezomib is a CYP3A4 substrate and not a clinically meaningful CYP3A4 inhibitor, so a pharmacokinetic effect on flibanserin is not expected. Both drugs can cause hypotension and dizziness, which may be additive.
What this interaction means in plain words
Bortezomib and Flibanserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bortezomib belongs to Oncology; Flibanserin belongs to Genitourinary.
Why it happens
No established pharmacokinetic mechanism; possible additive hypotensive effects.
What to do
Monitor blood pressure and dizziness in patients on bortezomib who take flibanserin. No dose change is routinely required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Bortezomib
- Apalutamide + Bortezomib Major
- Bortezomib + Carbamazepine Major
- Bortezomib + Etrasimod Major
- Bortezomib + Fosphenytoin Major
- Bortezomib + Idelalisib Major
- Bortezomib + Lonafarnib Major
Frequently asked questions
Can I take Bortezomib with Flibanserin?
MediHelp rates the interaction as minor. Bortezomib and Flibanserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bortezomib is a CYP3A4 substrate and not a clinically meaningful CYP3A4 inhibitor, so a pharmacokinetic effect on flibanserin is not expected. Both drugs can cause hypotension and dizziness, which may be additive.
How serious is the interaction between Bortezomib and Flibanserin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and dizziness in patients on bortezomib who take flibanserin. No dose change is routinely required.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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