Drug interactions
Bosutinib + Cetirizine
Severity: Minor
Bosutinib and Cetirizine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bosutinib may inhibit P-glycoprotein and could modestly increase cetirizine concentrations. The clinical consequence is likely small, such as slightly more drowsiness.
What this interaction means in plain words
Bosutinib and Cetirizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bosutinib belongs to Oncology; Cetirizine belongs to Respiratory.
Why it happens
Possible P-glycoprotein inhibition by bosutinib, reducing efflux of cetirizine.
What to do
Monitor for increased drowsiness; no empiric dose change is normally required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cetirizine
- Acrivastine + Cetirizine Moderate
- Amisulpride + Cetirizine Moderate
- Asenapine + Cetirizine Moderate
- Avapritinib + Cetirizine Moderate
- Benzhydrocodone / acetaminophen + Cetirizine Moderate
- Brexpiprazole + Cetirizine Moderate
Other interactions of Bosutinib
- Amiodarone + Bosutinib Major
- Apalutamide + Bosutinib Major
- Aprepitant + Bosutinib Major
- Bosentan + Bosutinib Major
- Bosutinib + Carbamazepine Major
- Bosutinib + Chlorpromazine Major
Frequently asked questions
Can I take Bosutinib with Cetirizine?
MediHelp rates the interaction as minor. Bosutinib and Cetirizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bosutinib may inhibit P-glycoprotein and could modestly increase cetirizine concentrations. The clinical consequence is likely small, such as slightly more drowsiness.
How serious is the interaction between Bosutinib and Cetirizine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased drowsiness; no empiric dose change is normally required.
What other medicines interact with Cetirizine?
MediHelp also lists interactions of Cetirizine with, for example, Acrivastine, Amisulpride, Asenapine. The full list is on the Cetirizine page.
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