Drug interactions
Amisulpride + Cetirizine
Severity: Moderate
Amisulpride and Cetirizine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amisulpride can cause drowsiness and cetirizine is mildly sedating in some patients. Taken together, they may increase somnolence and reduce alertness.
What this interaction means in plain words
Amisulpride and Cetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amisulpride belongs to Central Nervous System; Cetirizine belongs to Respiratory.
Why it happens
Additive CNS depressant effects.
What to do
Monitor for excess sedation and advise caution when driving; consider a non-sedating antihistamine if drowsiness occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cetirizine
- Acrivastine + Cetirizine Moderate
- Asenapine + Cetirizine Moderate
- Avapritinib + Cetirizine Moderate
- Benzhydrocodone / acetaminophen + Cetirizine Moderate
- Brexpiprazole + Cetirizine Moderate
- Brivaracetam + Cetirizine Moderate
Other interactions of Amisulpride
- Amiodarone + Amisulpride Contraindicated
- Amisulpride + Arsenic trioxide Contraindicated
- Amisulpride + Disopyramide Contraindicated
- Amisulpride + Dofetilide Contraindicated
- Amisulpride + Droperidol Contraindicated
- Amisulpride + Ibutilide Contraindicated
Frequently asked questions
Can I take Amisulpride with Cetirizine?
MediHelp rates the interaction as moderate. Amisulpride and Cetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amisulpride can cause drowsiness and cetirizine is mildly sedating in some patients. Taken together, they may increase somnolence and reduce alertness.
How serious is the interaction between Amisulpride and Cetirizine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excess sedation and advise caution when driving; consider a non-sedating antihistamine if drowsiness occurs.
What other medicines interact with Cetirizine?
MediHelp also lists interactions of Cetirizine with, for example, Acrivastine, Asenapine, Avapritinib. The full list is on the Cetirizine page.
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