Drug interactions
Brexpiprazole + Pomalidomide
Severity: Minor
Brexpiprazole and Pomalidomide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pomalidomide commonly causes fatigue, dizziness and somnolence, which may add to the sedation caused by brexpiprazole. The combination can impair alertness and increase the risk of falls.
What this interaction means in plain words
Brexpiprazole and Pomalidomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brexpiprazole belongs to Central Nervous System; Pomalidomide belongs to Miscellaneous.
Why it happens
Additive CNS-depressant effects; no pharmacokinetic interaction is established.
What to do
Monitor for drowsiness and dizziness, and advise caution with driving or machinery. Reduce doses if sedation becomes problematic.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Brexpiprazole
Other interactions of Pomalidomide
- Deferiprone + Pomalidomide Major
- Ethinyl estradiol-drospirenone + Pomalidomide Major
- Fluvoxamine + Pomalidomide Major
- Apalutamide + Pomalidomide Moderate
- Brivaracetam + Pomalidomide Moderate
- Carbamazepine + Pomalidomide Moderate
Frequently asked questions
Can I take Brexpiprazole with Pomalidomide?
MediHelp rates the interaction as minor. Brexpiprazole and Pomalidomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pomalidomide commonly causes fatigue, dizziness and somnolence, which may add to the sedation caused by brexpiprazole. The combination can impair alertness and increase the risk of falls.
How serious is the interaction between Brexpiprazole and Pomalidomide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for drowsiness and dizziness, and advise caution with driving or machinery. Reduce doses if sedation becomes problematic.
What other medicines interact with Brexpiprazole?
MediHelp also lists interactions of Brexpiprazole with, for example, Alfentanil, Amisulpride, Apalutamide. The full list is on the Brexpiprazole page.
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