Drug interactions
Bromocriptine + Phentermine
Severity: Moderate
Bromocriptine and Phentermine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can raise blood pressure and heart rate, and bromocriptine has been linked to hypertension and arrhythmias. Combined use may add to cardiovascular stimulation.
What this interaction means in plain words
Bromocriptine and Phentermine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bromocriptine belongs to Central Nervous System; Phentermine belongs to Central Nervous System.
Why it happens
Additive pharmacodynamic sympathomimetic and pressor effects.
What to do
Monitor blood pressure and heart rate, especially after starting or adjusting either drug. Stop phentermine if sustained hypertension or palpitations occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bromocriptine
Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Bromocriptine with Phentermine?
MediHelp rates the interaction as moderate. Bromocriptine and Phentermine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can raise blood pressure and heart rate, and bromocriptine has been linked to hypertension and arrhythmias. Combined use may add to cardiovascular stimulation.
How serious is the interaction between Bromocriptine and Phentermine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, especially after starting or adjusting either drug. Stop phentermine if sustained hypertension or palpitations occur.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Cobicistat. The full list is on the Bromocriptine page.
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