Drug interactions
Bromocriptine + Tecovirimat
Severity: Minor
Bromocriptine and Tecovirimat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tecovirimat is a weak CYP3A4 inducer and may slightly lower bromocriptine exposure. The effect is likely modest and of short duration given the usual treatment course.
What this interaction means in plain words
Bromocriptine and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bromocriptine belongs to Central Nervous System; Tecovirimat belongs to Miscellaneous.
Why it happens
Weak CYP3A4 induction by tecovirimat increases bromocriptine metabolism.
What to do
Monitor clinical response to bromocriptine during the tecovirimat course. Dose adjustment is rarely required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bromocriptine
Other interactions of Tecovirimat
- Bosentan + Tecovirimat Moderate
- Cyclosporin + Tecovirimat Moderate
- Darunavir + Tecovirimat Moderate
- Ethinyl estradiol-drospirenone + Tecovirimat Moderate
- Ethinyl estradiol-levonorgestrel + Tecovirimat Moderate
- Glimepiride-pioglitazone + Tecovirimat Moderate
Frequently asked questions
Can I take Bromocriptine with Tecovirimat?
MediHelp rates the interaction as minor. Bromocriptine and Tecovirimat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tecovirimat is a weak CYP3A4 inducer and may slightly lower bromocriptine exposure. The effect is likely modest and of short duration given the usual treatment course.
How serious is the interaction between Bromocriptine and Tecovirimat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to bromocriptine during the tecovirimat course. Dose adjustment is rarely required.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Cobicistat. The full list is on the Bromocriptine page.
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