Drug interactions
Brompheniramine + Fenfluramine
Severity: Minor
Brompheniramine and Fenfluramine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is sedating, whereas fenfluramine may cause either somnolence or reduced appetite and agitation. Their CNS effects may partially offset or add unpredictably. The clinical significance is unclear.
What this interaction means in plain words
Brompheniramine and Fenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brompheniramine belongs to Respiratory; Fenfluramine belongs to Central Nervous System.
Why it happens
Opposing or variable CNS effects; serotonergic activity of fenfluramine versus H1 blockade, with no established interaction.
What to do
Monitor the level of alertness and sedation after starting the combination. No dose change is routinely needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Brompheniramine
Other interactions of Fenfluramine
- Fenfluramine + Isocarboxazid Contraindicated
- Fenfluramine + Linezolid Contraindicated
- Fenfluramine + Phenelzine Contraindicated
- Fenfluramine + Selegiline Contraindicated
- Fenfluramine + Tranylcypromine Contraindicated
- Almotriptan + Fenfluramine Major
Frequently asked questions
Can I take Brompheniramine with Fenfluramine?
MediHelp rates the interaction as minor. Brompheniramine and Fenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brompheniramine is sedating, whereas fenfluramine may cause either somnolence or reduced appetite and agitation. Their CNS effects may partially offset or add unpredictably. The clinical significance is unclear.
How serious is the interaction between Brompheniramine and Fenfluramine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor the level of alertness and sedation after starting the combination. No dose change is routinely needed.
What other medicines interact with Brompheniramine?
MediHelp also lists interactions of Brompheniramine with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Brompheniramine page.
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