Drug interactions
Brompheniramine + Risperidone
Severity: Moderate
Brompheniramine and Risperidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is a sedating first-generation antihistamine with anticholinergic activity. With risperidone it may increase drowsiness, psychomotor impairment and anticholinergic effects.
What this interaction means in plain words
Brompheniramine and Risperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Risperidone belongs to Central Nervous System.
Why it happens
Additive CNS depression and anticholinergic effects.
What to do
Warn the patient about drowsiness and avoid driving if affected. Prefer a non-sedating second-generation antihistamine where possible, especially in older patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Risperidone
- Ibutilide + Risperidone Contraindicated
- Risperidone + Vandetanib Contraindicated
- Adagrasib + Risperidone Major
- Amiodarone + Risperidone Major
- Amisulpride + Risperidone Major
- Amoxapine + Risperidone Major
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Risperidone?
MediHelp rates the interaction as moderate. Brompheniramine and Risperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brompheniramine is a sedating first-generation antihistamine with anticholinergic activity. With risperidone it may increase drowsiness, psychomotor impairment and anticholinergic effects.
How serious is the interaction between Brompheniramine and Risperidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn the patient about drowsiness and avoid driving if affected. Prefer a non-sedating second-generation antihistamine where possible, especially in older patients.
What other medicines interact with Risperidone?
MediHelp also lists interactions of Risperidone with, for example, Ibutilide, Vandetanib, Adagrasib. The full list is on the Risperidone page.
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