Drug interactions
Budesonide-formoterol + Chloroquine
Severity: Moderate
Budesonide-formoterol and Chloroquine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine prolongs the QT interval and has been linked to torsades de pointes. Formoterol can add to QT prolongation and lower potassium, increasing arrhythmia risk.
What this interaction means in plain words
Budesonide-formoterol and Chloroquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Chloroquine belongs to Anti Parasitic.
Why it happens
Additive QT prolongation through chloroquine potassium channel blockade and beta2-agonist effects, with possible hypokalemia.
What to do
Check baseline ECG, potassium and magnesium before co-administration. Prefer a short-acting alternative or lower formoterol dose where possible and monitor for palpitations.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Chloroquine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Chloroquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine prolongs the QT interval and has been linked to torsades de pointes. Formoterol can add to QT prolongation and lower potassium, increasing arrhythmia risk.
How serious is the interaction between Budesonide-formoterol and Chloroquine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG, potassium and magnesium before co-administration. Prefer a short-acting alternative or lower formoterol dose where possible and monitor for palpitations.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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