Drug interactions
Budesonide-formoterol + Dolasetron
Severity: Moderate
Budesonide-formoterol and Dolasetron: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dolasetron's active metabolite prolongs PR, QRS and QT intervals, and formoterol can add to QTc prolongation. Together they increase the risk of arrhythmia, especially with hypokalemia or cardiac disease.
What this interaction means in plain words
Budesonide-formoterol and Dolasetron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Dolasetron belongs to Gastrointestinal Tract.
Why it happens
Additive effects on cardiac repolarization, plus beta2-agonist-induced hypokalemia.
What to do
Monitor ECG and correct electrolytes in at-risk patients. Consider a non-QT-prolonging antiemetic if risk factors are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Dolasetron
- Apomorphine + Dolasetron Contraindicated
- Dofetilide + Dolasetron Contraindicated
- Dolasetron + Ibutilide Contraindicated
- Dolasetron + Pimozide Contraindicated
- Dolasetron + Thioridazine Contraindicated
- Dolasetron + Vandetanib Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Dolasetron?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Dolasetron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dolasetron's active metabolite prolongs PR, QRS and QT intervals, and formoterol can add to QTc prolongation. Together they increase the risk of arrhythmia, especially with hypokalemia or cardiac disease.
How serious is the interaction between Budesonide-formoterol and Dolasetron?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct electrolytes in at-risk patients. Consider a non-QT-prolonging antiemetic if risk factors are present.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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