Drug interactions
Budesonide-formoterol + Gepirone
Severity: Moderate
Budesonide-formoterol and Gepirone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gepirone carries a QT prolongation warning and formoterol may also prolong QTc and lower potassium. Together they may increase the risk of ventricular arrhythmias, particularly in patients with cardiac risk factors.
What this interaction means in plain words
Budesonide-formoterol and Gepirone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Gepirone belongs to Central Nervous System.
Why it happens
Additive QT interval prolongation, with formoterol-related hypokalemia as a contributing factor.
What to do
Check baseline ECG and electrolytes in patients with cardiac risk factors and correct hypokalemia; use the lowest effective formoterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Gepirone
- Clarithromycin + Gepirone Contraindicated
- Gepirone + Isocarboxazid Contraindicated
- Gepirone + Itraconazole Contraindicated
- Gepirone + Ketoconazole Contraindicated
- Gepirone + Linezolid Contraindicated
- Gepirone + Phenelzine Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Gepirone?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Gepirone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gepirone carries a QT prolongation warning and formoterol may also prolong QTc and lower potassium. Together they may increase the risk of ventricular arrhythmias, particularly in patients with cardiac risk factors.
How serious is the interaction between Budesonide-formoterol and Gepirone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with cardiac risk factors and correct hypokalemia; use the lowest effective formoterol dose.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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