Drug interactions
Budesonide-formoterol + Midodrine
Severity: Moderate
Budesonide-formoterol and Midodrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Midodrine is an alpha-1 agonist that raises blood pressure, and formoterol adds sympathomimetic effects. Together they may increase blood pressure and heart rate more than either alone, which matters in patients with cardiovascular disease.
What this interaction means in plain words
Budesonide-formoterol and Midodrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Midodrine belongs to Miscellaneous.
Why it happens
Additive sympathomimetic effects from alpha-1 agonism by midodrine and beta-2 agonism by formoterol.
What to do
Monitor blood pressure, including supine readings, and heart rate. Adjust midodrine dose if hypertension or tachycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Midodrine
- Isocarboxazid + Midodrine Contraindicated
- Midodrine + Phenelzine Contraindicated
- Midodrine + Tranylcypromine Contraindicated
- Dextroamphetamine + Midodrine Major
- Dihydroergotamine intranasal + Midodrine Major
- Dihydroergotamine + Midodrine Major
Frequently asked questions
Can I take Budesonide-formoterol with Midodrine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Midodrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Midodrine is an alpha-1 agonist that raises blood pressure, and formoterol adds sympathomimetic effects. Together they may increase blood pressure and heart rate more than either alone, which matters in patients with cardiovascular disease.
How serious is the interaction between Budesonide-formoterol and Midodrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, including supine readings, and heart rate. Adjust midodrine dose if hypertension or tachycardia occurs.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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