Drug interactions
Budesonide-formoterol + Ondansetron
Severity: Moderate
Budesonide-formoterol and Ondansetron: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ondansetron prolongs the QT interval in a dose-dependent manner, and formoterol may add to this and lower potassium. The risk is higher with congenital long QT syndrome, electrolyte disturbance or heart disease.
What this interaction means in plain words
Budesonide-formoterol and Ondansetron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Ondansetron belongs to Gastrointestinal Tract.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia.
What to do
Avoid in congenital long QT syndrome and correct electrolytes beforehand. Use the lowest effective ondansetron dose and monitor ECG in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Ondansetron
- Apomorphine + Ondansetron Contraindicated
- Ondansetron + Thioridazine Contraindicated
- Ondansetron + Vandetanib Contraindicated
- Adagrasib + Ondansetron Major
- Amiodarone + Ondansetron Major
- Amisulpride + Ondansetron Major
Frequently asked questions
Can I take Budesonide-formoterol with Ondansetron?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Ondansetron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ondansetron prolongs the QT interval in a dose-dependent manner, and formoterol may add to this and lower potassium. The risk is higher with congenital long QT syndrome, electrolyte disturbance or heart disease.
How serious is the interaction between Budesonide-formoterol and Ondansetron?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in congenital long QT syndrome and correct electrolytes beforehand. Use the lowest effective ondansetron dose and monitor ECG in high-risk patients.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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