Drug interactions
Budesonide-formoterol + Risperidone
Severity: Moderate
Budesonide-formoterol and Risperidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Risperidone can prolong the QTc interval, and formoterol may add to this effect, particularly with hypokalemia. This may increase arrhythmia risk in patients with cardiac disease or other risk factors.
What this interaction means in plain words
Budesonide-formoterol and Risperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Risperidone belongs to Central Nervous System.
Why it happens
Additive QTc prolongation, with beta-2 agonist-induced hypokalemia as a contributing factor.
What to do
Monitor ECG and serum potassium in at-risk patients. Use the lowest effective formoterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Risperidone
- Ibutilide + Risperidone Contraindicated
- Risperidone + Vandetanib Contraindicated
- Adagrasib + Risperidone Major
- Amiodarone + Risperidone Major
- Amisulpride + Risperidone Major
- Amoxapine + Risperidone Major
Frequently asked questions
Can I take Budesonide-formoterol with Risperidone?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Risperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Risperidone can prolong the QTc interval, and formoterol may add to this effect, particularly with hypokalemia. This may increase arrhythmia risk in patients with cardiac disease or other risk factors.
How serious is the interaction between Budesonide-formoterol and Risperidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in at-risk patients. Use the lowest effective formoterol dose.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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