Drug interactions
Budesonide-formoterol + Stiripentol
Severity: Minor
Budesonide-formoterol and Stiripentol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Stiripentol inhibits P-glycoprotein and some CYP enzymes, which may raise budesonide exposure. Systemic exposure from inhaled budesonide is low, so clinically meaningful effects are unlikely.
What this interaction means in plain words
Budesonide-formoterol and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide-formoterol belongs to Respiratory; Stiripentol belongs to Central Nervous System.
Why it happens
Inhibition of P-glycoprotein efflux and possibly CYP3A4-mediated metabolism, increasing budesonide exposure.
What to do
No dose change is usually required. Watch for signs of corticosteroid excess with long-term high-dose use and reduce the budesonide dose if these occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide-formoterol
Other interactions of Stiripentol
Frequently asked questions
Can I take Budesonide-formoterol with Stiripentol?
MediHelp rates the interaction as minor. Budesonide-formoterol and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stiripentol inhibits P-glycoprotein and some CYP enzymes, which may raise budesonide exposure. Systemic exposure from inhaled budesonide is low, so clinically meaningful effects are unlikely.
How serious is the interaction between Budesonide-formoterol and Stiripentol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually required. Watch for signs of corticosteroid excess with long-term high-dose use and reduce the budesonide dose if these occur.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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