Drug interactions
Bumetanide + Formoterol-mometasone
Severity: Moderate
Bumetanide and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Formoterol, bumetanide and corticosteroids can each lower serum potassium, so together they may cause clinically important hypokalemia. This raises the risk of arrhythmia, particularly in patients with heart disease or on digoxin. The effect is greater with high beta-agonist doses.
What this interaction means in plain words
Bumetanide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bumetanide belongs to Cardiovascular; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive potassium lowering through beta-2-mediated intracellular shift, renal loss from the loop diuretic and mineralocorticoid activity of corticosteroids.
What to do
Monitor serum potassium and magnesium periodically, especially at initiation or during acute illness, and replace as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Bumetanide
Frequently asked questions
Can I take Bumetanide with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Bumetanide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Formoterol, bumetanide and corticosteroids can each lower serum potassium, so together they may cause clinically important hypokalemia. This raises the risk of arrhythmia, particularly in patients with heart disease or on digoxin. The effect is greater with high beta-agonist doses.
How serious is the interaction between Bumetanide and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium periodically, especially at initiation or during acute illness, and replace as needed.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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