Drug interactions
Butcher's broom + Silodosin
Severity: Minor
Butcher's broom and Silodosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Butcher's broom contains ruscogenins reported to have alpha-adrenergic agonist activity, which could in theory oppose the alpha-1 blockade of silodosin. The clinical relevance is unproven and no meaningful effect has been documented.
What this interaction means in plain words
Butcher's broom and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic antagonism between an alpha-1 antagonist and a herbal product with possible alpha-agonist activity.
What to do
No routine action is needed; if urinary symptoms worsen in a patient taking this herbal product, consider stopping it.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Silodosin
- Atazanavir + Silodosin Contraindicated
- Conivaptan + Silodosin Contraindicated
- Darunavir + Silodosin Contraindicated
- Fosamprenavir + Silodosin Contraindicated
- Indinavir + Silodosin Contraindicated
- Itraconazole + Silodosin Contraindicated
Frequently asked questions
Can I take Butcher's broom with Silodosin?
MediHelp rates the interaction as minor. Butcher's broom and Silodosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Butcher's broom contains ruscogenins reported to have alpha-adrenergic agonist activity, which could in theory oppose the alpha-1 blockade of silodosin. The clinical relevance is unproven and no meaningful effect has been documented.
How serious is the interaction between Butcher's broom and Silodosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; if urinary symptoms worsen in a patient taking this herbal product, consider stopping it.
What other medicines interact with Silodosin?
MediHelp also lists interactions of Silodosin with, for example, Atazanavir, Conivaptan, Darunavir. The full list is on the Silodosin page.
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