Drug interactions
Cabergoline + Solriamfetol
Severity: Moderate
Cabergoline and Solriamfetol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Solriamfetol, a dopamine and norepinephrine reuptake inhibitor, can raise blood pressure and heart rate. Cabergoline is a dopamine agonist that more often causes hypotension, so the net effect on blood pressure is unpredictable, and dopaminergic adverse effects such as insomnia or agitation may be additive.
What this interaction means in plain words
Cabergoline and Solriamfetol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabergoline belongs to Endocrine; Solriamfetol belongs to Central Nervous System.
Why it happens
Solriamfetol increases synaptic dopamine and norepinephrine, which may interact pharmacodynamically with dopamine receptor agonism.
What to do
Monitor blood pressure and heart rate when starting or changing doses. Adjust therapy if hypertension, tachycardia or psychiatric symptoms develop.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cabergoline
Other interactions of Solriamfetol
- Isocarboxazid + Solriamfetol Contraindicated
- Linezolid + Solriamfetol Contraindicated
- Phenelzine + Solriamfetol Contraindicated
- Procarbazine + Solriamfetol Contraindicated
- Rasagiline + Solriamfetol Contraindicated
- Safinamide + Solriamfetol Contraindicated
Frequently asked questions
Can I take Cabergoline with Solriamfetol?
MediHelp rates the interaction as moderate. Cabergoline and Solriamfetol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Solriamfetol, a dopamine and norepinephrine reuptake inhibitor, can raise blood pressure and heart rate. Cabergoline is a dopamine agonist that more often causes hypotension, so the net effect on blood pressure is unpredictable, and dopaminergic adverse effects such as insomnia or agitation may be additive.
How serious is the interaction between Cabergoline and Solriamfetol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or changing doses. Adjust therapy if hypertension, tachycardia or psychiatric symptoms develop.
What other medicines interact with Cabergoline?
MediHelp also lists interactions of Cabergoline with, for example, Benperidol, Chlorpromazine, Clarithromycin. The full list is on the Cabergoline page.
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