Drug interactions
Calcium carbonate + Cefdinir
Severity: Minor
Calcium carbonate and Cefdinir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefdinir absorption is reduced by antacids containing multivalent cations, and iron in particular forms complexes. Calcium carbonate has a smaller effect but may lower absorption somewhat.
What this interaction means in plain words
Calcium carbonate and Cefdinir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Cefdinir belongs to Anti Bacterial.
Why it happens
Cation complexation and raised gastric pH may reduce oral absorption of cefdinir.
What to do
Give cefdinir at least 2 hours before or after calcium carbonate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Cefdinir
- Aluminum hydroxide + Cefdinir Moderate
- Cefdinir + Cholera vaccine Moderate
- Cefdinir + Famotidine Moderate
- Cefdinir + Gentamicin Moderate
- Cefdinir + Microbiota Moderate
- Cefdinir + Nizatidine Moderate
Frequently asked questions
Can I take Calcium carbonate with Cefdinir?
MediHelp rates the interaction as minor. Calcium carbonate and Cefdinir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefdinir absorption is reduced by antacids containing multivalent cations, and iron in particular forms complexes. Calcium carbonate has a smaller effect but may lower absorption somewhat.
How serious is the interaction between Calcium carbonate and Cefdinir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give cefdinir at least 2 hours before or after calcium carbonate.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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