Drug interactions
Calcium carbonate + Dapsone
Severity: Minor
Calcium carbonate and Dapsone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dapsone absorption may be reduced in a less acidic stomach, but clinical evidence for an antacid effect is limited. Any reduction is generally modest.
What this interaction means in plain words
Calcium carbonate and Dapsone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Dapsone belongs to Anti Bacterial.
Why it happens
Higher gastric pH may reduce dapsone dissolution, a theoretical effect with inconsistent data.
What to do
Separate doses by about 2 hours and monitor response to dapsone if antacids are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Dapsone
- Bcg vaccine live + Dapsone Major
- Dapsone + Primaquine Major
- Apalutamide + Dapsone Moderate
- Belzutifan + Dapsone Moderate
- Bosentan + Dapsone Moderate
- Bupivacaine implant + Dapsone Moderate
Frequently asked questions
Can I take Calcium carbonate with Dapsone?
MediHelp rates the interaction as minor. Calcium carbonate and Dapsone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dapsone absorption may be reduced in a less acidic stomach, but clinical evidence for an antacid effect is limited. Any reduction is generally modest.
How serious is the interaction between Calcium carbonate and Dapsone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours and monitor response to dapsone if antacids are used regularly.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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