Drug interactions
Calcium carbonate + Rosuvastatin
Severity: Minor
Calcium carbonate and Rosuvastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids containing aluminium and magnesium reduce rosuvastatin exposure; calcium carbonate is not well studied but may have a similar small effect. The lipid-lowering impact is probably minor.
What this interaction means in plain words
Calcium carbonate and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Rosuvastatin belongs to Cardiovascular.
Why it happens
Possible binding or reduced absorption of rosuvastatin in the gut; mechanism not firmly established for calcium.
What to do
Separate by about 2 hours if convenient. Follow lipid levels as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Rosuvastatin
Frequently asked questions
Can I take Calcium carbonate with Rosuvastatin?
MediHelp rates the interaction as minor. Calcium carbonate and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids containing aluminium and magnesium reduce rosuvastatin exposure; calcium carbonate is not well studied but may have a similar small effect. The lipid-lowering impact is probably minor.
How serious is the interaction between Calcium carbonate and Rosuvastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate by about 2 hours if convenient. Follow lipid levels as usual.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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