Drug interactions
Glipizide-metformin + Lanreotide
Severity: Moderate
Glipizide-metformin and Lanreotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanreotide suppresses insulin, glucagon and growth hormone secretion, so it can either raise or lower blood glucose. Glucose control in diabetic patients may shift, and antidiabetic doses may need to be changed.
What this interaction means in plain words
Glipizide-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glipizide-metformin belongs to Endocrine; Lanreotide belongs to Endocrine.
Why it happens
Somatostatin analog inhibition of insulin and counter-regulatory hormone secretion changes glucose homeostasis.
What to do
Monitor blood glucose when lanreotide is started or the dose changed, and adjust glipizide or metformin as required.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Glipizide-metformin
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Canagliflozin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Dapagliflozin-metformin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
Frequently asked questions
Can I take Glipizide-metformin with Lanreotide?
MediHelp rates the interaction as moderate. Glipizide-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and growth hormone secretion, so it can either raise or lower blood glucose. Glucose control in diabetic patients may shift, and antidiabetic doses may need to be changed.
How serious is the interaction between Glipizide-metformin and Lanreotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when lanreotide is started or the dose changed, and adjust glipizide or metformin as required.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
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