Drug interactions

carbamazepine + lomitapide

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Severity: Major · Evidence level: Moderate

↓ lomitapide; loss of efficacy.

Mechanism of action

CYP3A induction.

Clinical management

Avoid combination.

Drug reference

References

Frequently asked questions

Can I take carbamazepine with lomitapide?

The interaction is rated: Major. ↓ lomitapide; loss of efficacy.

How serious is the interaction between carbamazepine and lomitapide?

The interaction is rated: Major. Evidence level: Moderate.

How is the interaction between carbamazepine and lomitapide managed?

Avoid combination.

Why do carbamazepine and lomitapide interact?

CYP3A induction.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions