Drug interactions
Carbinoxamine + Methamphetamine
Severity: Minor
Carbinoxamine and Methamphetamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbinoxamine is a sedating first-generation antihistamine with anticholinergic activity, whereas methamphetamine is a stimulant. The stimulant may partly offset drowsiness but the combination may increase tachycardia and anxiety. Net effects on alertness are unpredictable.
What this interaction means in plain words
Carbinoxamine and Methamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbinoxamine belongs to Respiratory; Methamphetamine belongs to Central Nervous System.
Why it happens
Opposing CNS effects, with additive anticholinergic and sympathomimetic effects on heart rate.
What to do
Monitor heart rate, blood pressure and alertness. Reassess the need for either drug if tachycardia or agitation appears.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Other interactions of Carbinoxamine
- Alprazolam + Carbinoxamine Moderate
- Amisulpride + Carbinoxamine Moderate
- Amitriptyline + Carbinoxamine Moderate
- Amobarbital + Carbinoxamine Moderate
- Asenapine + Carbinoxamine Moderate
- Azelastine-fluticasone + Carbinoxamine Moderate
Frequently asked questions
Can I take Carbinoxamine with Methamphetamine?
MediHelp rates the interaction as minor. Carbinoxamine and Methamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Carbinoxamine is a sedating first-generation antihistamine with anticholinergic activity, whereas methamphetamine is a stimulant. The stimulant may partly offset drowsiness but the combination may increase tachycardia and anxiety. Net effects on alertness are unpredictable.
How serious is the interaction between Carbinoxamine and Methamphetamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and alertness. Reassess the need for either drug if tachycardia or agitation appears.
What other medicines interact with Methamphetamine?
MediHelp also lists interactions of Methamphetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Methamphetamine page.
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